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Detox centers are equipped to ensure that even the worst withdrawals are handled correctly. There are very few drugs with potentially fatal withdrawal symptoms.

Withdrawals are different for everyone. No one can agree exactly what it feels like to go through withdrawal from drugs. But, most people who have detoxed from certain drugs agree which ones had the worst withdrawals.

Why Withdrawals Feel So Bad

Your body and brain are always trying to maintain homeostasis. Your body and brain are always trying to stay level and to keep things balanced.

When you eat too much sugar, your pancreas pumps insulin into body to reach normal levels again. If you continue to eat too much sugar your body cannot process sugar the same again and you get diabetes. Simple.

Different drugs mimic different chemicals in your brain. Opioids release dopamine, MDMA and ecstasy release serotonin, marijuana releases cannabinoids. Your brain has receptors for all these chemicals which is the reason you feel the effects of these drugs.

The problem is that your brain tries to reach homeostasis, so if you abuse heroin, your brain will be filled with dopamine, and if you have too much dopamine, your brain will stop creating it naturally. Now you quit, and your body and brain go into shock. It has to reach homeostasis again, so it signals cravings, so you will find the dopamine that it can no longer produce.

That is where withdrawals come from. The more pleasure the chemical delivers, the more dependent you become and the worse the withdrawal symptoms are.

Drugs with the Worst Withdrawals

  1. Heroin & Prescription Drugs

Motley Crue Guitarist Nikki Sixx called it “Heroin Hell”. There have been movies made that feature the withdrawal including The Man With The Golden Arm (1955), Basketball Diaries (1995) and Trainspotting (1996). Heroin is the worst withdrawal experience.

Withdrawal symptoms include:

  • Runny nose
  • Runny eyes
  • Diarrhea
  • Dehydration
  • Loss of appetite
  • Nausea
  • Physical pain
  • Insomnia

For the most part, opioid withdrawals cannot kill you. However, detoxing from any substance can be dangerous. Entering a detox facility will not only be safer but easier. Detox center may recommend using low doses of less powerful opiates like methadone to help opioid withdrawals. Opioid and Heroin detox can help.

Heroin withdrawal lasts up to 8 days. Withdrawal symptoms are the worst between 1 – 3 days after last use. The worst opiate withdrawal symptoms are also during this period.

The most powerful, dangerous and addictive prescription drugs are:

  • Fentanyl (Duragesic, Aqtic, Fentora, Sublimaze)
  • Oxycodone (OxyContin)
  • Extended-release morphine (MS Contin)
  • Meperidine (Demerol), Hydromorphone (Dilaudid)
  • Combination hydrocodone products (Vicodin, Lorcet, Lortab).

These drugs will slowly destroy your opioid system and compromise the way your brain produces endorphins. Most people feel very depressed and a lot of people may consider suicide. Call 1 (800)-273-8255 or visit The National Suicide Prevention Lifeline.

  1. Methamphetamine

Methamphetamine is highly addictive and daily users will feel the effects of coming down quite quickly. Withdrawing from meth can be painful. The stimulant releases a large amount of dopamine and serotonin which can make withdrawal feel like depression.

Withdrawal symptoms include:

  • Physical pain
  • Exhaustion
  • Loss in appetite
  • Insomnia
  • Anxiety

Meth withdrawals cannot kill you, but they can lead to temporary psychosis, extreme paranoia and panic which may cause the person withdrawing to make fatal errors in judgement.

The most powerful, dangerous and addictive prescription drugs are:

  • Crystal Meth
  • Speed
  • Dexedrine
  • Adderall

Meth detox is available and treatment can drastically help with the detox and rehabilitation process.

  1. Cocaine

Cocaine has a very short half-life, which means that withdrawal symptoms will begin within the first 90 minutes after the last dose.

Withdrawal symptoms include:

  • Physical pain
  • Exhaustion
  • Increased appetite
  • Insomnia
  • Anxiety
  • Drop in Libido
  • Slow thinking

Cocaine withdrawal will not lead to death in most cases, and cocaine detox centers can help anyone who wants to safely detox.

Symptoms will last for up to 10 days. The worst withdrawals symptoms will be felt in the first 2 days.

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